Proof of Concept of a Stimulator Based on AC Current Rectification for Neuroprosthetics

نویسندگان

  • L. Becerra-Fajardo
  • A. Ivorra
چکیده

For several years, researchers have developed techniques to replace and enhance the capabilities of our neural system by means of implantable electrical stimulation technologies. Even though important work has been done in this field, further progress must be accomplished in terms of miniaturization in order to ensure comfort, simpler surgical implantation procedures, and the capability of using multiple wireless smart stimulators for achieving more muscle recruitment. In the past, with the objective of accomplishing an unprecedented level of miniaturization, we have proposed the development of implantable stimulators that would act as rectifiers of AC current supplied by external electrodes. Here it is described the development and evaluation of an addressable stimulator based on discrete component technology as a proof-of-concept of the proposed method. This macroscopic version of the stimulator is capable of generating magnitude controlled bipolar pulses according to commands modulated in the AC current. Multiple evaluations were done to test the device, including DC current testing, in-vitro and in-vivo testing, concluding that the developed system is an effective proof-of-concept of the method proposed, being able to perform controlled electrical stimulation. Electrical current testing showed that anodal and cathodal currents were generated, and in-vivo testing showed the effective electrical stimulation of an anesthetized earthworm. It is concluded that the idea of developing smart rectifiers as implantable stimulators is feasible. This represents a first step towards the design of an implantable device with a miniaturization level without precedents.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mathematical Proof for the Minimized Stray Fields in Transformers Using Auxiliary Windings Based on State Equations for Evaluation of FEM Results

Stray magnetic field is one of the main issues in design of transformers, since it causes non-ideal behavior of transformers. One of the techniques is usually adopted to mitigate the unwanted stray magnetic field is the use of auxiliary windings creating a magnetic field opposite to the incident one giving rise to the reduction of the total magnetic fields. This paper presents a new mathematica...

متن کامل

Determination of Electric Field at Inception Based upon Current-Voltage Characteristics of AC Corona in Rod-Plane Gaps

This paper deals with the measurement of AC corona inception voltage, Vincp, at the tip of a rod electrode using a hemispherically-capped rod-plane electrode configuration for various rod radii with a short air gap. Effects of atmospheric pressure and temperature variation on Vincp are investigated experimentally. An empirical equation for the field form factors of the hemispherically cappe...

متن کامل

From Ion Current to Electroosmotic Flow Rectification in Asymmetric Nanopore Membranes

Asymmetrically shaped nanopores have been shown to rectify the ionic current flowing through pores in a fashion similar to a p-n junction in a solid-state diode. Such asymmetric nanopores include conical pores in polymeric membranes and pyramidal pores in mica membranes. We review here both theoretical and experimental aspects of this ion current rectification phenomenon. A simple intuitive mod...

متن کامل

ANOVELMONITORINGTECHNIQUE TO DEFINE CP CRITERIA FOR BURIED PIPELINES UNDER AC CORROSION CONDITION

Abstract: The risks of alternating current (AC) corrosion and overprotection increasingly demand new criteria forcathodically protected pipelines. To assess the risk of AC corrosion, new cathodic protection (CP) criteria have beenproposed based on DC/AC current densities measurements using coupons. The monitoring system designed for thisproject was based on the instant-off method, with steel co...

متن کامل

BAWA , GAURAV . A Switched Capacitor based Micro - stimulator for Deep Brain

BAWA, GAURAV. A Switched Capacitor based Micro-stimulator for Deep Brain Stimulation. (Under the direction of Dr. Maysam Ghovanloo and Dr. Leda Lunardi.) This thesis presents a novel technique for the development of an implantable stimulator for Deep Brain Stimulation. The key idea is to harvest energy from an inductive link using an efficient switching mechanism at the secondary side. To valid...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012